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PDGF-AB human rec.
Product code : PAN.CB-1109301
PAN.CB-1109301The term PDGF refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all me…
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PDGF-AB human rec.
Product description
The term€˜PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchyme-derived cells.
Aberrant expression is involved in certain cancers, fibro-proliferative disorders and atherosclerosis. The proteins also contribute to wound healing and neural regeneration. There are four members of the PDGF family€“ PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist€“ a short form that is soluble and a long form that is retained by the extracellular matrix.
PDGF AB human recombinant is a heterodimeric, non-glycosylated, polypeptide chain containing 234 amino acids consisting of 13.3 kDa alpha-chain and 12.2 kDa beta-chain having a total molecular mass of 25.5 kDa. PDGF-AB is purified by proprietary chromatographic techniques.
Synonyms: Glioma-derived growth factor, Osteosarcoma-derived growth factor
PDGF-AB human rec.
Product specifications
Packaging Unit
10µg
Brand
PAN Biotech
tariff code
29371900
Stock temperature condition
see datasheet
Category
Human Cytokines and Growth Factors
Sterile
Yes